Ongoing US study shows that IdeS allows for transplantation of highly sensitized patients
The ongoing Phase II study at Cedars Sinai Medical Center is an investigator-initiated study that is looking at the effects of IdeS in enabling kidney transplantation in highly sensitized kidney transplant patients. The study will eventually recruit up to 20 patients and of today a total of 10 patients have been treated and subsequently transplanted.
The conclusion from the initial evaluation is that IdeS treatment of highly sensitized (HS) patients completely eliminates donor specific antibodies (DSAs) present at transplant and allows for successful transplantation of HLA incompatible patients. IdeS is well tolerated without infusion-related side effects and no significant infections to date. IdeS may provide a rapid, effective and durable method to eliminate DSAs and transplant HS patients who are resistant to current desensitization (DES).
Professor Stanley Jordan will present data from all included patients in this study at the American Transplant Congress in Boston. A meeting abstract, including the first four patients, has been published ahead of the presentation at the ATC website:
The information in this press release is disclosed pursuant to the Swedish Securities Markets Act and/or the Swedish Financial Instruments Trading Act. The information was released for public disclosure on May 17, 2016 at 08.30 CET.
For further information, please contact:
Hansa Medical AB
Göran Arvidson, CEO
Mobile: 46 70-633 30 42